Swyer-James-MacLeod Syndrome

Swyer-James-MacLeod syndrome (SJMS), also known as Swyer-James syndrome or hyperlucent lung syndrome, is an uncommon syndrome of unilateral functional hypoplasia of the pulmonary vasculature and emphysema, with or without associated bronchiectasis.[1][2] The condition was first described simultaneously in the 1950s by a respiratory physician William Mathieson Macleod in England (1954) and by a physician Paul Robert Swyer and a radiologist George James in Canada (1953).[3][4] This rare lung condition is characterized by radiographic hyperlucent appearance of a single pulmonary lobe or the entire lung. It is considered to arise as a postinfectious complication of bronchiolitis obliterans in childhood.