Dnmt3a2 in the Nucleus Accumbens Shell Mediates Cue-Induced Cocaine-Seeking Behavior

One of the main obstacles in treating drug addiction is the high rates of relapse even after prolonged periods of abstinence. Neuronal adaptions play a major role in drug craving and relapse ([Kalivas and Volkow, 2005][1]). Many of these adaptions involve changes in gene expression ([Nestler, 2001][