Synthesize of biological active substances on base carbom oxides

2012 
New effective method of obtaining of drugs on basice hydroxybenzoic acids and esters of isovaleric acid (drug substances «Ethylic ether of α-bromisovaleric acid», «Salycilic acid», «p-Hydroxybenzoic acid» and drugs «Validolum», «Korvalolum», «p-Aminosalycilic acid») had been worked out. The methods based on catalytical isobutylene hydroalkoxycarbonylation reaction with carbon monoxide and alcohols and phenol carboxylation reaction with alkaline salts of ethylcarbonic acid, easily obtained from carbon dioxide.
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