NOVEL, RECYCLABLE, AND THERMALLY STABLE TASK-SPECIFIC IONIC LIQUID (TBA ACETATE) MEDIUM/CATALYST FOR THE SYNTHESIS OF INDOLYLIDINECYCLIC-1,3- AND -1,4-DIKETONES

Abstract A simple and efficient synthesis of indolylidinethiazolidnediones (3) and indolylidinecyclic-1,3-diketones (5) has been developed by reaction of indole-3-aldehyde (1) with thiazolidinedione (2) or cyclic-1,3-diketones (4) using tetra butyl ammonium acetate (TBAA) melt as novel, cost-effective, and recyclable ionic liquid under solvent-free green conditions at 100 °C for 15–20 min without additional use of catalyst. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource(s): Full experimental and spectral details.]