Catechol- O -Methyltransferase and UDP-Glucuronosyltransferases in the Metabolism of Baicalein in Different Species

Background Baicalein is the major bioactive flavonoid in some herb medicines and dietary plants; however, the detailed metabolism pathway of its major metabolite oroxylin A-7-O-β-d-glucuronide in human was not clear. It was important to illustrate the major metabolic enzymes that participate in its elimination for the clinic use of baicalein.