DEVELOPMENT AND EVALUATION OF ANTI-DANDRUFF HAIR GEL

2011 
In the present study, an attempt was made to develop Clotrimazole Anti-Dandruff hair gel. The different formulation were developed using polymers such as Corbopol 940, Corbopol 934, PEG 200 etc. These polymers were selected based on their use in gel formulation. All the formulations were evaluated Active Content, Physical appearance, P H , Viscosity, Extrudability, Antifungal activity, Drug release Profile, Compatibility and Stability study. In Stability study, formulation F7 was shows no appreciable changes as compared to other formulation during the study period of three months. Formulation F7 was shows maximum zone of inhibition to an Anti-fungal activity during in vitro study. Therefore F7 could be used as an effective formulation for Anti-Dandruff hair gel of clotrimazole as compared to other formulation.
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