HLA in Uros from Peru Titikaka Lake: Tiwanaku, Easter and Pacific Islanders

Abstract Uros people live in floating reed islands in Titikaka Lake in front of Puno town (Peru). They could have started Tiwanaku culture and shared genes and culture with Pacific Islanders; it is particularly relevant the giant hat covered men statues found in both Tiwanaku at Titikaka Lake shore and Easter Island (3,700 km far from Chile in Pacific Ocean).These giants monoliths are very similar one another and unique in America and Pacific Islands. The following HLA alleles are shared in a specifically high frequency between Uros and Pacific Islanders HLA-A∗24:02, HLA-B∗35:05, HLA-B∗48:01, HLA-DRB1∗04:03, HLA-DRB1∗08:02 and HLA-DRB1∗09:01. Uros also have 3 unique HLA haplotypes: A∗24:02 - B∗15:04 - DRB1∗14:02 - DQB1∗03:01, A∗68:01:02 - B∗35:05 - DRB1∗04:03 - DQB1∗03:02, A∗24:02 - B∗48:01 - DRB1∗04:03 - DQB1∗03:02. Also Uros seem to be one of the most ancient population in Titikaka Lake that could have started Tiwanaku culture. Prehistoric contacts between Amerindians and Pacific Islanders are strongly suggested by genetic and cultural traits.It is not discarded that Uros could have come from Pacific Islands: Uros show melanic skin and are dolicocephalic; in contrast, surrounding Aymara people have a clear skin and are brachicephalic. The Kon-Tiki project led by Thor Heyerdahl showed that a simple sailing is possible between Peru and Polynesia Islands; also, the most ancient skull found in America is of black origin: Luzia ,suggesting that first America peopling was also carried out by Black/coloured people.