Acetylcholinesterase inhibitors combined with memantine for moderate to severe Alzheimer's disease: a meta-analysis

Domink Glinz,Viktoria Gloy,Andreas U. Monsch,Reto W. Kressig,Chandni Patel,Kimberly Alba McCord,Zanfina Ademi,Yuki Tomonaga,Matthias Schwenkglenks,Heiner C. Bucher,Heike Raatz

Acetylcholinesterase inhibitors combined with memantine for moderate to severe Alzheimer's disease: a meta-analysis

2019

Domink Glinz
Viktoria Gloy
Andreas U. Monsch
Reto W. Kressig
Chandni Patel
Kimberly Alba McCord
Zanfina Ademi
Yuki Tomonaga
Matthias Schwenkglenks
Heiner C. Bucher
Heike Raatz

The clinical efficacy and safety of combination therapy with acetylcholinesterase inhibitors (AChEI) and memantine compared to AChEIs or memantine alone in patients with Alzheimer’s disease is inconclusive.

Keywords:

Intensive care medicine
Diabetes mellitus
Medicine
Combination therapy
Memantine
Dementia
Meta-analysis
Cholinesterase
Internal medicine
Disease
Acetylcholinesterase
Adverse effect
Randomized controlled trial
Relative risk
Clinical Global Impression

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