Quantitative Measurement of Three Phase Bone Scintigraphy in Stroke Patients with Complex Regional Pain Syndrome

Objective: To evaluate usefulness of quantitative measurement of three phase bone scintigraphy in assessing the complex regional pain syndrome (CRPS) after stroke using reference value in healthy adults. Method: Twenty nine stroke patients with CRPS and 15 stroke patients without CRPS underwent three phase bone scintigraphy (TPBS). Uptake ratio was calculated by isotope count of affected side divided in isotope count of unaffected side in each phase. Reference value was obtained in 13 healthy adults. The sensitivity and specificity of quantitative measurement of TPBS was assessed. Results: In the all phases of hand, uptake ratios of the CRPS group were significantly higher than non-CRPS group (p