Time outside targeted oxygen saturation range and retinopathy of prematurity

Summary Objective To better understand the impact of hypoxia and hyperoxia on neonatal morbidity and mortality, we examined the number of hypoxia and hyperoxia events as well as percentage of time spent outside oxygen saturation targets in relationship to threshold retinopathy of prematurity (tROP) and mortality in preterm infants. Study design Saturation data in 2-second sampling from pulse oximeters was prospectively collected in a single NICU. Average SaO 2 , low and high saturation events, duration of events, and percentage of time infants spent outside of oxygen saturation range were collected and analyzed continuously during the hospitalization. Results 102 infants Conclusions Information such as the duration and number of hypoxia and hyperoxia events, as well as total time outside the targeted saturation range, could be factored into assessing clinical interventions and research studies in the prevention, treatment and evaluation of neonatal outcomes. © 2014 Elsevier Ireland Ltd. All rights reserved.