Extraction and Antioxidant Activity of Alkaloid from Selaginella involvens

In this study,the alkaloid components were extracted from Selaginella involvens,and identified by spectrophotometry and precipitation methods. The scavenging effect of S. involvens alkaloid on DPPH free radical was observed. The effects of S. involvens alkaloid on activities of total antioxidant activity( T-AOC),nitric oxide synthase( NOS) and content of malondialdehyde( MDA) in liver homogenate of rat were evaluated. The results revealed that S. involvens alkaloid had relative strong antioxidant capacity. S. involvens alkaloid scavenged DPPH free radical in a dose-dependent manner.In addition,S. involvens alkaloid increased the abilities of T-AOC and inhibited NOS as well as the content of MDA in liver homogenate of rat.