Titulação de aloanticorpos anti-a e anti-b em gatos domésticos sem raça definida em Porto Alegre, Rio Grande do Sul, Brasil
2011
The probability of occurrence of a transfusion reaction in a cat depends on the local prevalence of feline blood types and alloantibody titres. Determination of alloantibody titres assists in estimating the risk and the severity of transfusion reactions following an unmatched transfusion in a cat population. The objective of this study was to determine alloantibody titres and the risk of a possible transfusion reaction in non-pedigree domestic cats in Porto Alegre , Brazil. One hundred clinically healthy non-pedigree and non-related cats with no history of previous transfusion were randomly selected. Blood samples were collected from the jugular vein and the alloantibody titres were determined by tube serial dilution of the serum from cats with known blood types, the estimated risk was calculated according previous studies. In the present study, 82.5% and 100% of types A and B cats, respectively, showed varied alloantibodies titres. Based on the titres found in the present study, the risk of an acute severe reaction is 33.3% and an acute mild reaction is 66.7% in a type B cat transfused with blood type A or AB. In type A cats transfused with blood type AB or B, the risk of an acute severe reaction is 1.0%, an acute mild reaction is 37.1% and premature red cell destruction is 44.3%.
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