Situation and clinical application of antibody detection for Coronavirus Disease 19/ 新型冠状病毒特异性抗体检测现状及应用思考

With the gradual progress of epidemic prevention and control work, the process of epidemic prevention and control in Coronavirus Disease 19(COVID-19) has entered a critical period As the main method to diagnose patients with COVID-19, the disadvantages of nucleic acid detection are gradually revealed As an important immune response product, specific antibodies have been rapidly applied to the laboratory detection of 2019 Novel Coronavirus (2019-nCoV), combined with nucleic acid detection for rapid diagnosis and screening of patients with COVID-19 This paper explores and discusses the production pattern and common detection methods of 2019-nCoV specific antibodies and the application and limitations of antibody detection in the clinical work to promote the application and development of specific antibody in COVID-19 diagnosis