Control of Drug-Resistant TB

Drug-resistant TB (DR-TB) refers to the infection of Mtb that is resistant to at least one anti-tuberculosis drug. The occurrence of DR-TB is caused by non-standardized treatment and/or insufficient management of patient with TB. Most of initially treated patient with non DR-TB can be cured by regular treatment of first-line anti-tuberculosis drug for 6 months. But inappropriate medication of anti-tuberculosis drugs (such as intermittent medication or inappropriate dosage) or early retrieval of anti-tuberculosis drug can induce resistance to anti-tuberculosis drug. And Mtb resistant to anti-tuberculosis drug further causes spread of DR-TB. The spread of drug-resistant Mtb in patients with DR-TB is an important way for spread of DR-TB. The prevalence and spread of drug-resistant Mtb present challenges to the global TB control. Especially along with the formation of global village, diversified flowing of populations for business, travelling, and purchase aggravates the prevalence of DR-TB.