Serum IgG antibodies to a 35-kDa P0-related glycoprotein in motor neuron disease

Abstract Using an immunoblot technique we found a significantly higher frequence of serum IgG antibodies to a 35-kDa peripheral nerve myelin glycoprotein in patients with motor neuron disease (MND) (39% of 70) than in patients with neuropathy (13% of 61), other neurological diseases (9% of 32) and normal subjects (5% of 20) ( P