Molecular Adjuvants Based on Nonpyrogenic Lipophilic Derivatives of norAbuMDP/GMDP Formulated in Nanoliposomes: Stimulation of Innate and Adaptive Immunity

Pavlína Knötigová,Daniel Zyka,Josef Mašek,Anna Kovalova,Michal Křupka,Eliška Bartheldyová,Pavel Kulich,Štěpán Koudelka,Róbert Lukáč,Zuzana Kauerová,A. Vacek,Milada Horynova,Alois Kozubík,Andrew D. Miller,Ladislav Fekete,Irena Kratochvílová,Jan Ježek,Miroslav Ledvina,Milan Raska,Jaroslav Turánek

Molecular Adjuvants Based on Nonpyrogenic Lipophilic Derivatives of norAbuMDP/GMDP Formulated in Nanoliposomes: Stimulation of Innate and Adaptive Immunity

2015

Purpose The aim of this work was to demonstrate an immunostimulatory and adjuvant effect of new apyrogenic lipophilic derivatives of norAbuMDP and norAbuGMDP formulated in nanoliposomes.

Keywords:

Liposome
Adjuvant
Acquired immune system
Muramyl dipeptide
Immunology
Chemistry
Stimulation
Biochemistry
pharmacology toxicology

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