Suspension of active substance orally.
1999
Pharmaceutical composition in the form of an applicable suspension orally, comprising a) an active substance of the NSAID type selected from the group of propionic acid derivatives, the acetic acid derivatives, derivatives of fenaminico acid derivatives biphenylcarboxylic acid, the acid enolcarboxamidas of heterocycles diaryl substituents methylsulfonyl or aminosulfonyl and the acid sulphonamides and the pharmaceutically acceptable salts thereof, wherein the active substance a spectrum of the grain size wherein at least 90% of particles is less than 50 im, b) a physiologically indifferent dispersion in which the solubility of the active substance is less than 500 ig / ml, c) 0.1 to 5% by weight of highly dispersed silicon dioxide with a specific surface area of at least 50 m2 / g, which is incorporated in the dispersion medium with shear force application characterized by Speed idad peripheral rotor 15 to 35 m / s, d) 0.05 to 2% by weight of a soluble cellulose ether in pharmaceutical grade water.
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