Polyherbal effects of Berberius lycium and Hedra helix on Alloxan monohydrate induced diabetes

Diabetes mellitus ia endocrinological disorder caused by insulin deficiency. This disease was present over million years ago. Diabetes main reason is the disturbance in release of the insulin by pancrease. Many scientific drugs are used now a days like metformin etc. But these medications on the other hand had side effects too. So for this polyherbal drugs should be used having no side effects. When metformin is compared to the herb Berberis lycium it was observed that the alkaloid berberine was more effective than metformin. Hypoglycemic effects are assessed on normal rabbits and in those rabbits in which diabetes is induced by alloxan monohydrate. Then the combine effects of the extracts of the Berberis lyceum and Hedera helix on alloxan monohydrate induced rabbits was observed. After one week treatment blood glucose level was checked significant results observed. Previous data from different experimentation revealed that aqueous extract of polyherbal drug is more effective in reducing blood glucose level than methanolic herbal extracts or scientific medications. The main centre of attention of  this review is to elaborate the polyherbal drug development for diabetes instead of medications like metformin.