Cp*RhIII-Catalyzed Sulfonamide-Directed Ortho Arene C–H Carbenoid Functionalization with Pyridotriazoles

In this Letter, triazoles as carbene reagents were used for sulfonamide-directed C–H insertion carbenoid functionalization to construct benzylpyridine sulfonamide dual-pharmacophore compounds. This method is simple and efficient and can be used for the late-stage modification of sulfonamide drugs.