Polydatin effectively attenuates disease activity in lupus-prone mouse models by blocking ROS-mediated NET formation
2018
Background
Neutrophil extracellular trap (NET) formation has been described to be closely involved in the pathogenesis of systemic lupus erythematosus (SLE). In this study, we aimed to investigate the effect of polydatin (PD) on NET formation and its effects on disease activity in lupus-prone mouse models.
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