Diabetes and coronary disease: a need for new therapies for an expanding disease burden.

The prevalence of diabetes mellitus (DM) has nearly doubled in the adult population of the United States from 4.5% in 1995 to 8.2% in 2010 ([1][1]). Patients with DM are more likely to develop cardiovascular disease, have shorter life expectancy ([2][2]), and have higher mortality from acute