Slow-release composition of aripiprazole and derivative thereof and preparation method thereof

The invention discloses a slow-release composition of aripiprazole and derivative thereof and a preparation method thereof. The non-solvent form of the slow-release composition of aripiprazole and derivative thereof is prepared from raw materials including aripiprazole or aripiprazole derivative and water-insoluble polymer. The slow-release composition of aripiprazole and derivative thereof disclosed by the invention avoids obvious phenomenon of release lag or burst release after administration to realize a good slow-release property, and can maintain stable therapeutic plasma concentration in several weeks or longer time; and moreover, with relatively high stability, the slow-release composition still can maintain the slow release behavior after long-time storage.