THRESHOLD FRACTION ANISOTROPY LEVEL AND VASCULAR DEMENTIA PREDICTION FOR SUBJECTS WITH DIAGNOSED ENCEPHALOPATHY

As a consequence of the cerebral tracts’ damages, encephalopathy comes with cognitive disorders. Diffusion-tensor MRI is a cerebral tracts’ integrity quantitative measurement method. The main purpose of the study was to develop criteria of cerebral tracts integrity using DT-MRI to predict vascular dementia, to find threshold CFA level in liable tracts to measure dementia risk. DT-MR results were compared with neuropsychological tests of subjects with diagnosed encephalopathy. Identified statistically significant (р<0,005) FA decrease in three regions for those subjects with cognitive impairment: front sections of corona radiata, inferior longitudinal fasciculi and anterior horn of internal capsule. Threshold FA level calculated for these 3 region of interests, they can be predictors of the risk of cognitive disorders for subjects with diagnosed encephalopathy.