CIPROFLOXACIN INDUCED SYSTEMIC LUPUS ERYTHEMATOSUS

Article history This is a case report of 13 year old female patient, who was on Ciprofloxacin and Piroxicam tablets for the treatment of fever. Purpuric rash were developed all over the body on the 5 th day from drug administration. The patient was then admitted to intensive care unit at a hospital, where her condition was diagnosed as Idiopathic Thrombocytic Purpura (ITP) or vasculitis. Later it was found that, the patient was suffering from "Drug Induced Lupus (DIL)", and the drug behind the reaction was suspected to be Ciprofloxacin. The patient was experiencing purpura rash all over the body and pustular rash all around the mouth with low levels of platelets. Ciprofloxacin induced lupus is very rarely observed, the present ADR has scored 5 on naranjo scale and is severe according to Hartwig and Siegel scale of causality assessment.