Anti-Brownian ELectrokinetic (ABEL) Trapping of Single High Density Lipoprotein (HDL) Particles

Samuel Bockenhauer,Alexandre Fürstenberg,Quan Wang,Michael P. Bokoch,Xiao Jie Yao,Brian T. DeVree,Roger K. Sunahara,Brian K. Kobilka,W. E. Moerner

Anti-Brownian ELectrokinetic (ABEL) Trapping of Single High Density Lipoprotein (HDL) Particles

2009

Samuel Bockenhauer
Alexandre Fürstenberg
Quan Wang
Michael P. Bokoch
Xiao Jie Yao
Brian T. DeVree
Roger K. Sunahara
Brian K. Kobilka
W. E. Moerner

The Anti-Brownian ELectrokinetic (ABEL) trap uses voltage feedback to electrokinetically cancel the Brownian motion of single particles in solution in microfluidic geometries. This allows trapping of single high density lipoprotein (HDL) particles for extended observation.

Keywords:

Brownian motion
Electrokinetic phenomena
High-density lipoprotein
Analytical chemistry
Nuclear magnetic resonance
Chemistry
Molecular physics
Trapping
Microfluidics

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