Translesion synthesis genes POLI and REV1 in breast tumors and response to neoadjuvant chemotherapy.

Patricia A. Thompson,Emma V. Jones,Christina Preece,Jinyu Li,Jigna Bhalla,Jules Cohen,Lea N. Baer,Andrew Pierce,Alison T. Stopeck

Translesion synthesis genes POLI and REV1 in breast tumors and response to neoadjuvant chemotherapy.

2020

Patricia A. Thompson
Emma V. Jones
Christina Preece
Jinyu Li
Jigna Bhalla
Jules Cohen
Lea N. Baer
Andrew Pierce
Alison T. Stopeck

e12642Background: Translesion synthesis (TLS) of DNA by specialized polymerases (POLs) and REV1, a scaffold protein that recruits other TLS DNA POLs for nascent strand extension, experimentally ena...

Keywords:

Gene
POLI
Chemotherapy
Pathology
REV1
Cancer research
Medicine
DNA
Polymerase
Scaffold protein

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