125 Strain and strain rate for evaluating of right ventricular functional profile in patients with COPD and metabolic syndrome

Background The association between COPD and metabolic syndrome (MS) are frequently seen in daily clinical practice, but the cardiac impact on right ventricular (RV) functional profile using strain and strain rate of free wall is poorly studied in this group of patients. Methods Thirty-two patients with COPD (FEV1 = 48.9 ± 0.4; sPAP = 32.8 ± 0.4; 6-MWD = 391.9 ± 3.9) was compared with thirty-one patients with COPD and MS (FEV1 = 42.8 ± 0.8; sPAP = 32.8 ± 0.4; 6-MWD = 391.9 ± 3.9) regarding right ventricular systolic strain and strain rate. Longitudinal strain and strain rate analysis in the basal and mid segments of lateral wall of RV were performed in both groups using Velocity Vector Imaging technique. All results are expressed as mean ± SE using 15.0 SPSS version. Results Strain and strain rate in all segments of RV lateral wall were significantly decreased in COPD and MS group (strain basal and mid: −23.3 ± 0.2 respectively −22.4 ± 0.2; strain rate basal and mid: −1.4 ± 0.0 respectively −1.2 ± 0.0) compared with COPD alone (strain basal and mid: −18.6 ± 0.2 respectively −16.8 ± 0.2; strain rate basal and mid: −1.2 ± 0.0 respectively −1.0 ± 0.0) (p  Conclusions The assessment of strain and strain rate of free wall of RV is a good clinical tool in evaluating of right functional cardiac profile and may be in prediction of exercise capacity in patients with COPD and MS.