The anticaries effects of low fluoride formulations of toothpaste may be different in caries-active and caries-inactive children.

Article Title and Bibliographic Information Low-fluoride dentifrice and caries lesion control in children with different caries experience: a randomized clinical trial. Lima TJ, Ribeiro CC, Tenuta LM, Cury JA. Caries Res 2008;42(1):46-50. Level of Evidence Level 2: Limited-quality, patient-oriented evidence. Strength of Recommendation Grade Not applicable. Purpose/Question How does caries status compare in caries-active and caries-inactive children aged 2 to 4 after using low-fluoride (500 μg F/g) or conventional fluoride (1100 μg F/g) toothpaste for 12 months in an area with low levels of fluoride in the water Source of Funding Not stated but toothpaste and brushes for the study provided by Colgate-Palmolive. Type of Study/Design Randomized controlled trial.