Method for preparing acetsalicylamide

2008 
The present invention relates to a method for preparing actylamide, in particular to a novel acylation method for preparing actylamide by using triethyl ammonium-alchlor (C2H5)3NHCl-nAL3 (n is equal to 2.0 minus 2.5) ion liquid as a catalyst and a solvent to catalyze salicylamide. The method is characterized in that in the presence of nitrogen, acetyl chloride is added to undergo synthesis reaction when the temperature of the salicylamide reactant in the ion liquid rises to between 32 and 46 DEG C. The method has the advantages that the obtained actylamide is high in conversion rate, good in selectivity, and high in purity, the reaction time of the process is short, the method is economic in resources, low in risk and toxicity, low in contamination, easy to control reaction conditions, and easy and simple in the process, and the like.
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