Facile, efficient synthesis of polysubstituted thiazoles via α-nitroepoxides and thioureas
2016
Abstract An efficient synthesis of 2,4,5-trisubstituted thiazoles via the reaction of α-nitroepoxides and thioureas under mild conditions has been developed. This reaction proceeded well at room temperature, to afford products in excellent yields for a wide range of substrate, and a possible mechanism has also been proposed.
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