Tribulus terrestris Hydroalcoholic Extract Administration Effects on Reproductive Parameters and Serum Level of Glucose in Diabetic Male Rats Efectos de la Administración del Extracto Hidroalcohólico Tribulus terrestris sobre los Parámetros Reproductivos y el Nivel Sérico de Glucosa en Ratas Macho Diabéticas

GHANBARI, A.; MORADI, M.; RAOOFI, A.; FALAHI, M. & SEYDI, S. Tribulus terrestris hydroalcoholic extract administrationeffects on reproductive parameters and serum level of glucose in diabetic male rats. Int. J. Morphol.,34(2):796-803, 2016.SUMMARY: Usage of medicinal plants for the treatment of diseases is a remarkable strategy considered in both clinical andexperimental studies. This study was conducted to evaluate the effect of Tribulus terrestris hydroalcoholic extract administration on theserum level of glucose and reproductive parameters in diabetic male rats. In this experimental study, 30 adult male Wistar rats (200–250g) were divided into 5 groups (n= 6). Diabetes was induced by a single intraperitoneal injection of 50 mg/kg streptozotocin. Ex perimen-tal groups received daily Intraperitoneal injection of the extract (100, 250 and 500 mg/kg) since one week after inducing diabe tes for twoweeks. At the end of the experiment, the serum levels of testosterone and glucose were examined by ELISA and Glucodr devicesrespectively. Sperm parameters including morphology, count and motility were evaluated from the cauda epididymis. The diameters ofseminiferous tubules were assessed based on 5 µm paraffin section of HE Glucose; Rat; Streptozotocin; Testosterone; Tribulus terrestris.