Use as 4-oxoquinoline compound and a hiv integrase inhibitors

To provide an anti-HIV agent having an HIV integrase inhibitory activity. A the following general formula [I] [Formula 1] (Wherein each symbol is as defined in the description.) Relates to 4-oxoquinoline compound or a pharmaceutically acceptable salt thereof represented by and anti-HIV agent comprising these compounds. The compounds of the present invention has an effect of inhibiting the HIV integrase activity, it is useful as AIDS therapeutic agent or preventive agent as an anti-HIV agent. Moreover, protease inhibitors, the combination with other anti-HIV agents such as reverse transcriptase inhibitors, can be a more effective anti-HIV agents. Also, it has a high inhibitory activity specific for integrase can be a safe fewer side effects drug to the human body. .BACKGROUND