Antibacterial Activity of Fibrous Deoxyaminocellulose.

Fibrous deoxyaminocelluloses (DACs) with degree of substitution by amino group up to 0.11 were prepared by the nucleophilic substitution of deoxybromocellulose (DBC), which had prepared from cotton fiber, with ammonia in dimethylsulfoxide. A certain amount of unsubstituted bromine residue remained in obtained DAC. Antibacterial activity of acetic acid salt of the fibrous DAC was examined on three bacteria. For Esherichia coli, DAC showed good antibacterial activity, although the bromine residue in DAC was deduced to contribute to the activity more than amino group. For Staphylococcus aureus, DAC showed excellent antibacterial activity, where the amino group in DAC contributed to the activity more than bromine residue. For Klebsiella pneumoniae, the antibacterial activity of DAC was rather lower than that for the former two bacteria, but still the activity was enough to pass JIS L 1902-1998 as a antibacterial fiber.