Association between oxidized low-density lipoprotion receptor-1(LOX-1), hypertension and hyperlipemia

Expression of LOX-1 is very low in normal physiological conditions, but it can be heightened by many factors. LOX-1 interacts with eNOS, renin-angiotensin-aldosterone system, endothelin 1 and endothelin converting enzyme 1, resulting in hypertension's occurance and development which interact with hyperlipemia through LOX-1.