Isolation and study of the properties of the hemagglutinins produced by Streptomyces badius actinomycetes

: Hemagglutinin inducing polyagglutination of erythrocytes in the presence of the group blood sera was isolated from the supernatant of the culture fluid of Streptomyces badius 0626 by precipitation with ammonium sulfate and subsequent chromatography on Sephadex. Hemagglutinin proved to be a protein containing no lipid or carbohydrate components and possessing no bacterioagglutinating ability. Examination of the culture fluid supernatants of 150 cultures did not reveal any strains definitely exhibiting the transformation capability for human blood groups.