Ulcerative terminal ileitis after BCG therapy for bladder carcinoma.

Aim:  We evaluated the aetiology of ulcerative ileitis in a 77-year-old patient receiving BCG therapy for recurring bladder carcinoma. Methods and results:  Histological examination, laboratory data and the clinical history allowed us to exclude a classical cause such as Crohn's disease, tuberculosis or ischaemia. The important locoregional reaction suggests a BCG ileitis of the terminal ileum. Intestinal BCG ileitis has been exceptionally described after BCG vaccination. Conclusion:  Our observation of ulcerative ileitis indicates that a digestive tract location is possible as a reaction to BCG therapy.