Abstract 14787: Loss of Wnt7a is Associated With Reduced Vegf-a/vegfr2 Mediated Endothelial Tip Cell Formation and Angiogenesis in Pulmonary Arterial Hypertension

Ananya Chakraborty,Abinaya Nathan,Mark Orcholski,Stuti Agarwal,Elya Shamskou,Joyce Yu,Alden Mallory,Jose A. Acosta,Roberto Gunzman,Ke Yuan,Vanesa Rojas,Joseph T. Crossno,Lai Ming Yung,Paul B. Yu,Thomas E. Spencer,Robert A. Winn,Vinicio A. de Jesus Perez

Abstract 14787: Loss of Wnt7a is Associated With Reduced Vegf-a/vegfr2 Mediated Endothelial Tip Cell Formation and Angiogenesis in Pulmonary Arterial Hypertension

2020

Ananya Chakraborty
Abinaya Nathan
Mark Orcholski
Stuti Agarwal
Elya Shamskou
Joyce Yu
Alden Mallory
Jose A. Acosta
Roberto Gunzman
Ke Yuan
Vanesa Rojas
Joseph T. Crossno
Lai Ming Yung
Paul B. Yu
Thomas E. Spencer
Robert A. Winn
Vinicio A. de Jesus Perez

Rationale: Pulmonary arterial hypertension (PAH) is characterized by loss of microvessels. The Wnt pathways control pulmonary angiogenesis but their role in PAH is incompletely understood. Objectiv...

Keywords:

WNT7A
Angiogenesis
Cancer research
tip cell
VEGF receptors
Medicine

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