Synthesis of the Gold Glyconanoparticles Based on 6-Deoxy- and 2-(Acetylamino)aldoses 3-Thiopropionylhydrazones
2021
A method for the synthesis of gold glyconanoparticles with average particle size of 18–21 nm and low polydispersity index based on readily available thiolated compounds: 3-thiopropionylhydrazones of L-fucose, L-rhamnose, N-acetyl-D-glucosamine, and N-acetyl-D-mannosamine has been developed. It has been shown that some of the gold glyconanoparticles exhibit antitumor activity, and the initial thiolated glycoligands have shown strong radioprotective activity, increasing the survival rate of mortally irradiated mice by 50–70%.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
36
References
0
Citations
NaN
KQI