Abstract 1453: LXR-623, a novel Liver X Receptor modulator, displays neutral lipid effects in Cholesteryl Ester Transfer Protein-expressing species and inhibits atherosclerotic lesion progression in Low Density Lipoprotein receptor knockout mice

2007

LXRα and LXRα are ligand-activated transcription factors involved in the upregulation of genes involved in reverse cholesterol transport (RCT), a process involved in cholesterol homeostasis. Unfort...

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