Detection of Alzheimer's disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein.

Bin Ji,Maiko Ono,Tomoteru Yamasaki,Masayuki Fujinaga,Ming-Rong Zhang,Chie Seki,Ichio Aoki,Seiji Kito,Makoto Sawada,Tetsuya Suhara,Naruhiko Sahara,Makoto Higuchi

Detection of Alzheimer's disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein.

2021

Bin Ji
Maiko Ono
Tomoteru Yamasaki
Masayuki Fujinaga
Ming-Rong Zhang
Chie Seki
Ichio Aoki
Seiji Kito
Makoto Sawada
Tetsuya Suhara
Naruhiko Sahara
Makoto Higuchi

A substantial and constitutive expression of translocator protein (TSPO) in cerebral blood vessels hampers the sensitive detection of neuroinflammation characterized by greatly induced TSPO express...

Keywords:

Translocator protein
Disease
Cancer research
Neuroinflammation
pet ligand
Radioligand
Chemistry

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