A trial of a burn wound treatment employing autografting of cultured keratinocytes

Epidermal sheets prepared from cultured keratinocytes were autografted to a burn wound on a 71-year-old woman. Grafted epidermis seemed to be well accepted during the first 2 months; however, a significant portion peeled off after blisters formed. Ultimately, 24% of the grafted epidermis survived and thrived.