Up conversion nanotubes with tunable fluorescence properties based on Gd2O2S:Ln3+ (Ln3+=Yb3+,Er3+) and derivatives for photodynamic therapy
2020
In this study, Gd2O2S:Ln3+ (Ln3+ = Yb3+, Er3+) upconversion nanotubes (UCNTs) were synthesised by using Gd(OH)3:Ln3+ (Ln3+ = Yb3+, Er3+) nanotubes as the template. The luminescent and biological properties of Gd2O2S:Ln3+ (Ln3+ = Yb3+, Er3+) UCNTs, along with photodynamic therapy (PDT) applications of the Gd2O2S:8%Yb3+,2%Er3+ UCNT-Ce6 (chlorin e6) nanocomposites, were systematically studied. The resultant UCNTs showed excellent biocompatibility with human retinal pigment cells (ARPE-19) even after a prolonged incubation time of 72 h, and could be used as luminescent probes. Microscopic imaging revealed that the UCNTs existed mainly in cytoplasm. PDT studies on the Gd2O2S:8%Yb3+,2%Er3+ UCNT-Ce6 nanocomposites indicate that the growth of the tumour (cell) could be inhibited dramatically when it was injected (incubated) with Gd2O2S:8%Yb3+,2%Er3+ UCNT-Ce6 nanocomposites under the irradiation of 980 nm laser.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
38
References
1
Citations
NaN
KQI