Clinical Study of BBK8 on Gentamicin (GM) Resistant Gram Negative Rods (GNR)

1. Incidence of resistant strains of GNR against B-lactam antibiotics was higher in strains isolated from urine and blood rather than from sputum, especially in those isolated from blood. 2. Also, Gentamicin resistant strains were isolated more frequently from urine and blood than from sputum. 3. Strains of Proteus, Klebsiella and Pseudomonas which are resistant to Gentamicin have been increased in past two years. 4. Gentamicin resistant strains of GNR did not show the cross resistance to Amikacin (BBK8). 5. Amikacin showed therapeutic effect on P.aeruginosa septicemia which was highly resistant to Gentamicin and on Proteus mirabillis septicemia.