Primary vascular pulmonary hypertension and ovulation inhibitors

: The case of a 32-year-old woman who had used oral contraceptives and died from primary vascular pulmonary-hypertension (PVPH) is discussed. A case of this type had never been reported before and the relationship between the occurrence of PVPH and oral contraceptive use is discussed. A relationship between oral contraceptive use and venous thrombosis of the lower extremities has been demonstrated. The direct effect of oral contraceptives on blood vessels has been shown in animal experiments and pathological-histological studies. Clinical studies indicate a relationship between pulmonary hypertension and oral contraceptive use.