Palladium-Catalyzed Allylic Alkylation Using Pyridino-Oxazolines and Quinolino-Oxazolines as Ligands — Influence of Steric Factors.

Abstract Four new chiral pyridino- and quinolino-oxazolines were subjected to the palladium-catalyzed alkylation of 1,3-diphenyl-2-propenyl acetate. The enantioselectivity varied (82–88% ee) with the steric properties of the ligands. The results are discussed in connection with results previously obtained using analogous ligands.