Cytopathological diagnosis of metastatic pleomorphic liposarcoma in the lung: A report of a case correlated with the histopathology of the primary tumour

Pleomorphic liposarcoma (PLS) is morphologically defined by the presence of pleomorphic lipoblasts in a background of high-grade sarcoma. Representing the rarest variant of liposarcoma, PLS frequently metastasizes, most commonly to the lungs. We present the case of a 72-year-old male patient with pulmonary metastatic PLS. The primary tumour was located in the back thoracic wall. Cytopathological confirmation of the metastasis to the lung was offered using bronchoscopical sampling methods. Bronchial brushing and washing of the visible metastatic lesion revealed pleomorphic spindle-shaped cells of high-grade sarcoma with occasional lipoblasts. Diagn. Cytopathol. 2009. © 2009 Wiley-Liss, Inc.