Complete assignment of the stereostructure of a new squalene-derived epoxy tri-THF diol from Spathelia glabrescens by total synthesis

Abstract The total assignment of the incomplete stereostructure of a new squalene-derived epoxy tri-tetrahydrofuran (THF) diol ( 2 ) to the structural formula 3 has been achieved through the first asymmetric syntheses of (22 S )- 3 and its epimer (22 R )- 4 .