Characteristics of an established epithelial cell line (RL-19) from rat liver

Summary An established epithelial cell line obtained from 10-day-old rat liver is described. The cytogenic examination revealed a pseudodiploid karyotype with two marker chromosomes. The cells were checked for neoplastic transformation. No transformations occurred within more than two years of subcultivation. Among some enzymes searched for, catalase, 5'-nucleotidase, and catechol-0-methyltransferase activities were detected.