Abstract 12672: More Than 40% of Hypertensive Sleep Apnea Turned to Normotensive by Continuous Positive Airway Pressure Therapy Along With More Substantial Benefit in Having Morning Hypertension

Background: Sleep apnea (SAS) elevates blood pressure (BP) and is one of important causes of resistant hypertension (HT). Continuous positive airway pressure therapy (CPAP) decreases BP in SAS patients. However, the impact of CPAP on BP in hypertensive SAS patients is still obscure. This study is to examine the hypothesis that (1) BP lowering effect of CPAP is more prominent on morning BP than on evening BP in hypertensive SAS patients, and (2) a high percentage of hypertensive SAS patients especially of having morning HT turn to normotensive by CPAP. Methods: Ninety-three hypertensive SAS patients (74 males, 19 females, age 57.0+/-14.1, BMI 27.2+/-5.3) treated by CPAP were included. All patients were undertaken polysomnography before and after CPAP application and measured morning and evening BP in each occasion. CPAP was applied in patients with apnea-hypoxia index (AHI) > 20. Mean duration of CPAP was 32.7+/-26.1 days. Central SAS shared only 2.1% in these patients. HT was defined as SBP of ≥140 and/or...