11C-Methionine-PET for Evaluation of Carbon Ion Radiotherapy in Patients with Pelvic Recurrence of Rectal Cancer

Purpose Progress of the novel carbon ion radiotherapy (CIRT) in the treatment of cancers has created the need for a method to accurately evaluate the response. We investigated whether l-[11C]methyl-methionine (11C-methionine) uptake at pre- and post-CIRT could be an early response predictor in patients with pelvic recurrence of rectal cancer.